A New Direction in Flu Prevention: Exploring Alternatives to the Annual Shot 

Rethinking Flu Protection 

Every year, we hear the same advice: get your flu shot, wash your hands, stay home if you’re sick. And while these steps are still important, science is exploring new ways to keep people healthy—especially for those who might need extra protection. 

At M3 Wake Research, we’re preparing to study a new option that could help prevent the flu after you’ve already been exposed, especially from someone in your own household. This isn’t a vaccine — it’s a different kind of medicine that may offer fast, short-term protection. 

What’s Different About This Approach? 

Most flu vaccines work by training your immune system to recognize the flu virus before you’re exposed. But this new method, using something called a monoclonal antibody, works differently. Instead of teaching your body to fight the flu over time, it gives you ready-made protection right away. 

Think of it like a security guard posted at your door before the virus gets in. This is especially helpful for: 

  • People who can’t get vaccinated 
  • People with weaker immune systems 
  • Families or caregivers exposed to the flu at home 
Clinical trial participant receiving a vaccine

Why Now? 

Flu season can hit fast and hard. Sometimes, you don’t have time to get a vaccine or wait for it to work. Other times, you’re around someone sick before you even know it. 

This new option is designed to be given after you’ve been around someone with the flu, such as a family member, roommate, or loved one, before you get sick yourself. The goal is to reduce the chances of getting sick, even after exposure. 

How Flu Prevention Has Evolved

Scientist testing medical treatments in a laboratory

It’s amazing to see how far we’ve come in flu care over the years: 

  • Then: Basic vaccines, limited options, and fewer protections. 
  • Recent past: Updated yearly vaccines, nasal sprays, antiviral medications
  • Now: Monoclonal antibody research. 

But the goal hasn’t changed: to keep more people healthy and reduce the spread of illness in our communities. 

Staying Protected: What Still Works 

While new options are exciting, traditional flu prevention still plays a huge role in keeping you and your family safe. These simple steps are always helpful: 

  • Wash your hands, often, with soap and water 
  • Cover your mouth when coughing or sneezing 
  • Stay home if you’re feeling under the weather 
  • Clean high-touch surfaces like doorknobs and counters 
  • Get your annual flu shot — it’s still one of the best ways to protect yourself 

Even if you’re considering newer options, combining them with these habits offers the best protection. 

Who Might Benefit From This Research? 

Our upcoming study is designed for individuals who live with someone who has flu symptoms and hasn’t been vaccinated. If you’ve recently been around someone with the flu but you’re still feeling okay, this could be a great opportunity to help researchers learn more about preventing illness in real time. 

This includes: 

  • Children (ages 5 and up) 
  • Adults living with or caring for sick family members 
  • People who haven’t had their flu vaccine yet this season 

The goal is to learn whether this medication can help prevent flu symptoms after exposure—especially in household settings, where flu spreads quickly. 

What’s Next? 

Right now, we’re preparing to open this study soon. We’ll be sharing more details about who can participate and how the process works. When the time comes, you’ll be able to sign up for a quick screening, learn about the study medication, and decide if it’s a good fit for you or your family. 

For now, we just want to keep you informed. If you’re curious about flu prevention beyond the shot, or you’re interested in helping advance research, this could be a great opportunity. 

Be Part of the Next Potential Medication for Flu Prevention

Flu prevention is changing, and at M3 Wake Research, we’re excited to be part of something new. Whether you stick with traditional protection or explore new options, what matters most is staying healthy and helping science move forward. 

Stay tuned for more updates, and thank you for being part of a community that cares about better health for everyone.

Clinical trial site team