The Science Behind Behavioral Health Disorders

While many people may not understand the distinction between mental health and behavioral health disorders, there are some conditions that are classified as both. These conditions are classified as both mental health and behavioral health disorders because they include both mental aspects and physical behaviors that correlate to the thought patterns displayed by individuals with these conditions. The primary conditions that fall into both mental and behavioral health include:  

  • Obsessive-Compulsive Disorder (OCD) 
  • Binge Eating Disorder 
  • Major Depressive Disorder 

Additionally, while not considered a mental health disorder, epilepsy is a neurological condition that causes individuals to experience seizures based on potential physical, physiological, and environmental triggers. At M3 Wake Research, we are regularly accepting individuals for a variety of behavioral health disorders and neurological conditions. If you have been diagnosed with any of these conditions and are seeking advanced options, consider applying to one of our clinical trials. 

Understanding Obsessive-Compulsive Disorder (OCD) in Mental Health

What is OCD? 

Obsessive-Compulsive Disorder (OCD) is a chronic mental health condition characterized by recurring, unwanted thoughts (obsessions) and repetitive behaviors (compulsions) that the individual feels compelled to perform. These obsessions and compulsions can interfere significantly with daily life and activities.  

Symptoms of OCD

  • Obsessions: Intrusive, irrational thoughts, images, or urges that cause significant anxiety. Common obsessions include fear of contamination, fear of harming oneself or others, and a need for symmetry or exactness.  
  • Compulsions: Repetitive behaviors or mental acts that a person feels driven to perform in response to an obsession or according to rigid rules. Common compulsions include excessive handwashing, checking things repeatedly, and counting or repeating words silently.  

Risk Factors and Causes

The exact cause of OCD is not fully understood, but several factors are believed to contribute:  

  • Genetic Factors: Family history of OCD or other anxiety disorders can increase the risk.  
  • Brain Structure and Functioning: Abnormalities in certain areas of the brain, particularly those involved in decision-making and response inhibition.  
  • Environmental Factors: Stressful life events, trauma, and infections can trigger or exacerbate OCD symptoms.  

Exploring Binge Eating Disorder and Other Eating Disorders

What is Binge Eating Disorder?  

Binge Eating Disorder (BED) is a severe, life-threatening, and treatable eating disorder characterized by recurrent episodes of eating large quantities of food, often very quickly and to the point of discomfort. These episodes are typically accompanied by a feeling of loss of control and are followed by feelings of shame or guilt.

Symptoms of Binge Eating Disorder

  • Eating Large Amounts of Food: Consuming an unusually large amount of food within a specific period.  
  • Loss of Control: Feeling unable to stop eating or control what or how much one is eating.  
  • Eating Rapidly: Eating much more quickly than normal during binge episodes.  
  • Eating in Secret: Often eating alone or in secret due to embarrassment.  
  • Feeling Distressed: Experiencing feelings of shame, guilt, or distress after binge eating.  

Risk Factors and Causes

Several factors can increase the risk of developing BED:  

  • Genetics: Family history of eating disorders can increase risk.  
  • Psychological Factors: Emotional trauma, low self-esteem, and body dissatisfaction.  
  • Dieting: History of restrictive dieting or yo-yo dieting.  
  • Biological Factors: Hormonal irregularities and genetic mutations that regulate appetite and food intake.  

Understanding Major Depressive Disorder and Depression Disorders  

Major Depressive Disorder (MDD) and other depression-related disorders are mental and behavioral health conditions that can significantly impact a person’s life, including mood, thinking, behavior, and overall function. People diagnosed with MDD and other depression disorders may experience a variance in severity and duration of the symptoms. However, with all depression disorders, individuals may experience persistent sadness, a loss of interest or pleasure in daily activities, and impaired functioning. 

What is Major Depressive Disorder (MDD)?   

Major Depressive Disorder, or MDD, often referred to as clinical depression, is a mood disorder characterized by a persistent feeling of sadness or loss of interest in most daily activities, including those that were once pleasurable. 

Symptoms and Causes of MDD  

In order for a professional to diagnose MDD, the symptoms typically must be present in an individual for at least two weeks.  

  • Mood-related symptoms: Persistent sadness, emptiness, or hopelessness. 
  • Cognitive: Feelings of worthlessness or guilt, and difficulty concentrating and/or making decisions. 
  • Physical: Changes in sleep patterns, such as insomnia or oversleeping, fatigue, significant changes in weight, either gaining or losing weight. 
  • Behavioral: Loss of interest in activities once enjoyed (anhedonia), social withdrawal, reduced ability to function in work, school, or social settings. 
  • Other: Suicidal thoughts or tendencies (in severe cases). 

The current medical understanding of MDD is that causes of the condition are a combination of genetic, biological, environmental, and psychological factors. It’s believed that trauma, stress, or any kind of loss can trigger episodes, but there is sometimes no clear cause for these episodes.  

Treatment of MDD    

Treatment for Major Depressive Disorder often involves a combination of psychotherapy (e.g., cognitive-behavioral therapy or CBT) and antidepressant medications (e.g., SSRIs, SNRIs). While these are the current standard treatment options, our research teams at M3 Wake Research are regularly accepting potential participants for upcoming MDD clinical trials, which aim to test potential new treatments and therapies. If you’re seeking advanced treatment options, consider applying to our clinical trials. 

Types of Depression Disorders 

There are a variety of depressive disorders that may affect an individual, and though some are more common or well-known than others, physicians and research professionals continue to learn more about these disorders through clinical trials and studies. Common depressive disorders include:  

  • Persistent Depressive Disorder (PDD), or Dysthymia 
  • Bi-polar Disorder (previously known as Manic-Depressive Disorder) 
  • Seasonal Affective Disorder (SAD) 
  • Post-partum Depression (PPD) 
  • Atypical Depression 
  • Psychotic Depression 
  • Premenstrual Dysphoric Disorder (PMDD) 

If you or someone you love has been diagnosed with any depressive condition, including Major Depressive Disorder (MDD), consider applying for one of our openly-enrolling clinical trials to help increase knowledge around these conditions and test potential new treatments and therapies that may improve patient outcomes.  

Understanding Epilepsy and Other Mental Disorders 

What is Epilepsy?   

Epilepsy is a neurological disorder marked by recurrent, unprovoked seizures due to abnormal electrical activity in the brain. Seizures can vary in type and severity, ranging from brief lapses in attention or muscle jerks to severe and prolonged convulsions.  

What is Epilepsy?   

  • Seizures: The primary symptom of epilepsy, which can be categorized as:  
    • Generalized Seizures: Affect both sides of the brain and include tonic-clonic (grand mal) seizures, absence seizures, and myoclonic seizures.  
    • Focal Seizures: Originate in one area of the brain and include simple focal seizures, complex focal seizures, and secondary generalized seizures.  
  • Other Symptoms: Temporary confusion, staring spells, uncontrollable jerking movements, loss of consciousness, and psychic symptoms like fear or déjà vu.  

Risk Factors and Causes   

Several factors can contribute to the development of epilepsy: 

  • Genetic Influence: Certain types of epilepsy run in families, indicating a genetic component. 
  • Brain Conditions: Brain tumors, strokes, and traumatic brain injuries can cause epilepsy. 
  • Infectious Diseases: Meningitis, encephalitis, and AIDS. 
  • Prenatal Injury: Brain damage before birth due to infections, poor nutrition, or oxygen deficiencies. 
  • Developmental Disorders: Autism and neurofibromatosis can increase the risk. 
  • Mental Illnesses: Various mental illnesses, including sleep-related problems and dementia, can increase the risk of developing epilepsy. 
  • Substance Abuse: Substance abuse is another significant risk factor for epilepsy. 

The Science of Mental Health Disorders

Neurobiology and Genetics 

Mental and behavioral health disorders are intricate conditions influenced by a myriad of factors, including neurobiology and genetics. Research has illuminated that these disorders are often linked to changes in brain structure and function, as well as genetic variations that can heighten an individual’s susceptibility. 

Neurobiology plays a pivotal role in the onset and persistence of mental and behavioral health disorders. For instance, studies have revealed that individuals with depression often exhibit altered levels of neurotransmitters such as serotonin and dopamine. Similarly, those with anxiety disorders may show changes in the amygdala, a brain region crucial for emotional processing. 

Genetics also significantly contribute to the development of mental health disorders. Many of these conditions have a robust genetic component, with specific genetic variations increasing the risk. For example, individuals with a family history of bipolar disorder are more likely to develop the disorder themselves. 

Understanding the neurobiology and genetics of mental health disorders is essential for crafting effective treatments and interventions. By pinpointing the underlying biological mechanisms, researchers and clinicians can develop targeted therapies that address the root causes of these conditions. 

Behavioral Health Across the Life Span

Developmental Factors  

Behavioral health is a vital component of overall well-being, influenced by various developmental factors throughout the life span. From childhood to old age, individuals encounter different challenges and experiences that can impact their behavioral health. 

  • In childhood, factors such as family dynamics, parenting styles, and social relationships play a crucial role. For instance, children who experience trauma or neglect are at a higher risk of developing mental and behavioral health disorders like anxiety or depression. 
  • During adolescence, peer relationships, academic pressures, and social media use become significant. Adolescents facing bullying or social isolation may be more prone to mental health conditions, such as depression, anxiety, or other conditions. 
  • In adulthood, work-life balance, relationships, and life transitions are key factors. Adults experiencing chronic stress or burnout are more likely to develop mental health disorders like depression, anxiety, addiction, or other conditions. 
  • In older age, factors such as retirement, social isolation, and cognitive decline come into play. Older adults dealing with loneliness or cognitive decline are at a higher risk of developing mental health disorders such as depression or anxiety. 

Understanding these developmental factors is crucial for developing effective interventions and treatments. By addressing the unique challenges of each life stage, clinicians and researchers can promote healthy behavioral health and prevent mental health disorders. 

Technology and Behavioral Health 

Technology is increasingly becoming a cornerstone in supporting behavioral health, with the potential to revolutionize mental health services. From telehealth to mobile apps, technology offers convenient and accessible tools for managing mental health. 

Telehealth, for instance, enables individuals to access mental health services remotely, which is particularly beneficial for those in rural areas or with mobility issues. Mobile apps provide tools and resources for managing mental health, including mood tracking, cognitive-behavioral therapy, and mindfulness exercises. 

Technology also supports behavioral health in other innovative ways: 

  • Online support groups and forums 
  • Virtual reality therapy 
  • Artificial intelligence-powered chatbots 
  • Wearable devices that track mental health metrics 

However, it’s essential to recognize the limitations of technology. It should complement, not replace, traditional mental and behavioral health services. Human interaction remains crucial, and access to trained mental health professionals is indispensable. 

Overall, technology holds immense potential to transform mental health services. By harnessing its power, we can promote healthy behavioral health and prevent mental health disorders. 

Consider Joining a Clinical Trial to Increase Our Understanding of Behavioral Health Disorders 

If you or someone you love has been diagnosed with any of the behavioral health disorders described above, considering applying for one of our actively enrolling clinical studies. Our research teams at M3 Wake Research are focused on finding potentially cutting-edge treatments and therapies that could help to increase our understanding of behavioral health conditions and advance medical and psychological science while improving patient outcomes for future generations.  

Discuss the available clinical trials for your condition with your primary care provider and apply for our trials today. Our team will follow up if you’re qualified for one of our enrolling clinical trials in the United States.