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Your Local Research Partner
M3 Wake Research Charleston is a distinguished site within the M3 Wake Research network, renowned for its commitment to excellence in conducting a wide range of clinical studies in the Southeast.
Currently Enrolling Studies & Specialties in the Charleston, South Carolina, Area
With over 45 years of combined experience across a wide range of therapeutic areas and specialties, M3 Wake Research Charleston offers opportunities to participate in clinical trials that support advancing care. Explore current studies to learn more and see if you may qualify.
If you are interested in a specialty or study not currently listed, complete our general survey to stay up-to-date with current and upcoming studies.
Currently Enrolling Clinical Trial Specialties
What Participants Are Saying
The staff have been exceptional, every step was organized, and professional, full explanation of each procedure. And kept me well-informed. I had such an exceptional experience; I look forward to being part of a future study. Many thanks to all.
— Kathy Forest
M3 Wake Research was always efficient. My appointments were always on time. The visits and calls were thorough. Being able to call anytime with questions and concerns made my participation easy. I look forward to more studies in the future.
— Teresa Starks
M3 Wake Research was very efficient, friendly, and professional. I was happy to be involved in this clinical study. I encourage anyone interested in clinical studies to give them a try. It was a great experience, plus I got the added benefits of receiving the vaccine.
— Diane Matranga
They were all very great, professional, courteous, nice, and very friendly. They treated me awesome and took care of me very efficiently.
— Harold Kessee
The staff was very accommodating with scheduling. I appreciate their flexibility with changes to my appointments. Also, I never got bruised from blood draws. The clinical staff is experienced and thoughtful. I feel well taken care of. Thank you!
— Patrick Yeung
Meet the Team
Our Investigators
Our principal investigators at M3 Wake Research Charleston are board-certified in their areas of specialty and highly experienced in clinical research. With our experienced principal investigators leading every clinical trial we support at our Charleston research site, we are dedicated to ensuring not only the integrity of every clinical trial, but also the collection of data to sufficiently study the medical device, treatment or therapy being tested. Meet our principal investigators who’ll be conducting the clinical trials at M3 Wake Research Charleston.
Donald Hurley, DO, FAAFP, DABFM
Principal Investigator
Family Medicine
A U.S. Veteran and board-certified family physician with over 35 years in Charleston and 25 years in research. Dr. Hurley is affiliated with Roper St. Francis, MUSC, Trident Medical Center, and the Mayo Clinic Care Network. His leadership combines community-based care, preventive medicine, and academic mentorship, making him a highly credible and connected research investigator.
Cayce Tangeman, MD
Principal Investigator
Family Medicine
Board-certified family medicine physician affiliated with Roper Hospital, with over 20 years in practice and 5 years of clinical trial experience.
Operational Leadership
Crystal Dyer
Site Director
8 years of clinical research experience
Crystal offers extensive experience across a conducting a wide variety of clinical trials. Crystal is known for her collaborative approach and deep connection to the community. Additionally, Crystal has achieved Pfizer Site Excellence as a site in 2021.
Partner with M3 Wake Research in Charleston, SC
High standards of trial conduct & patient care
M3 Wake Research Charleston, as part of the M3 Wake Research network, specializes in conducting clinical trials with a focus on patient safety and scientific integrity. Our collaboration ensures access to a range of therapeutic areas, maintaining the high standards of trial conduct and patient care through our network’s robust quality assurance and protocol standardization.
Cutting edge of medical research
By partnering with M3 Wake Research Charleston, healthcare providers can offer their patients access to pioneering treatments across various medical disciplines. Our clinical trials in the Lowcountry represent the cutting edge of medical research, providing new avenues for patient care. This partnership benefits patient health outcomes, and underscores your practice’s dedication to innovation and quality care.
News & Updates
Understanding Graves’ Disease: An Autoimmune Thyroid Disorder
September 30, 2025
Now Enrolling: Obesity and Type 2 Diabetes Studies at M3 Wake Research…
September 22, 2025
Understanding Obesity: A Deep Dive into Its Causes, Consequences &…
September 19, 2025
Clinical Research in the Community: Why Partnering with Community Phys…
September 11, 2025
Join Our Research Studies
Contact M3 Wake Research Charleston in Charleston, South Carolina
Whether you are a patient, caregiver, or a physician, clinical trials are available in the Charleston, South Carolina, area for a variety of focus areas. Our team at M3 Wake Research Charleston provides the highest quality research studies to advance the medical field and find innovative treatments and therapies.
Use our Find a Trial tool or search by indication and your location to find a clinical trial that may be relevant to your condition. If you need assistance or have any questions, please contact us directly.